Assistant Professor Daphne Weihs

Research Interests:

Cancer cell biomechanics for diagnostics and pretension of metastasis

Short Synopsis:

Structure and mechanics of live cells in relation to cancer progression and diagnosis. Diagnosis of cellular health and cancer response to treatments through intracellular mechanics and cell-substrate interactions. Relation of substrate stiffness to cancer metastasis formation, specifically extravasation and cell dormancy. Rheology and microrheology of complex fluids.

5. Moti Umansky and Daphne Weihs, “Novel Algorithm and MATLAB-Based Program for Automated Power Law Analysis of Single Particle, Time-Dependent Mean-Square Displacement”, Computer Physics Communications 183, 1783-1792 (2012).
6. Naama Gal and Daphne Weihs, “Intracellular mechanics and activity of breast cancer cells correlate with metastatic potential”, Cell Biochemistry and Biophysics 63(3), 199-209 (2012). Featured in: Mammary Cell News, Vol. 4.18 (May 10, 2012).
7. Daphne Weihs, Tal Hadad, Roi Gurka, and Alex Liberzon, “Flexible blade rheometer for in-line measurement of viscosity”, Chemical Engineering Science 91, 130-133 (2013).
8. Shada Abuhattum and Daphne Weihs, “Cell-based coordinate system for intracellular location-dependent particle tracking analysis”, Online First. Invited contribution to a Special Issue of Computer Methods in Biomechanics and Biomedical Engineering.
9. Revital Kristal-Muscal, Liron Dvir, and Daphne Weihs, “Metastatic cancer cells tenaciously indent impenetrable, soft substrates”, New Journal of Physics, Focus Issue on Physics of Cancer, 15, 035022 (2013).